Detailed description page of Hmrbase2

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11531 details
Primary information
ID11531
Uniprot IDP41159
DescriptionLeptin;Alternative Name- Obesity factor;Alternative Name- Obese protein; Precursor
OrganismHomo sapiens
TxonomyEukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea (apes); Hominidae (great apes); Homininae; Homo; Homo sapiens (Human)
Subcellular LocationSecreted
Developmental StageNA
SimilarityBelongs to the leptin family.
Tissue SpecificityNA
Post Translational ModificationNA
FunctionMay function as part of a signaling pathway that acts to regulate the size of the body fat depot. An increase in the level of LEP may act directly or indirectly on the CNS to inhibit food intake and/or regulate energy expenditure as part of a homeostatic mechanism to maintain constancy of the adipose mass.
Length167
Molecular Weight18641
NameLeptin
SequenceNA
Sequence mapNA
PDB ID1AX8
DrugpediaNA
ReceptorP48357;P48357;O95214;O15243;A8K2E3;Q6FHL5;Q6FHL7
DomainNA
Pharmaceutical UseNA