Detailed description page of Hmrbase2

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11494 details
Primary information
ID11494
Uniprot IDP67930
DescriptionSomatotropin precursor (Growth hormone).
OrganismOvis aries
TxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Caprinae; Ovis.
Subcellular LocationSecreted
Developmental StageNA
SimilarityBelongs to the somatotropin/prolactin family.
Tissue SpecificityNA
Post Translational ModificationNA
FunctionPlays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues
Length217
Molecular Weight24631
NameSomatotropin
SequenceFPAMSLSGLFANAVLRAQHLHQLAADTFKEFERTYIPEGQRYSIQNTQVAFCFSETIPAPTGKNEAQQKSDLELLRISLLLIQSWLGPLQFLSRVFTNSLVFGTSDRVYEKLKDLEEGILALMRELEDVTPRAGQILKQTYDKFDTNMRSDDALLKNYGLLSCFRKDLHKTETYLRVMKCRRFGEASCAF
Sequence map190 (28-217)
PDB IDNA
DrugpediaNA
ReceptorQ28575
DomainNA
Pharmaceutical UseNA