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11450 details
Primary information
ID11450
Uniprot IDP41520
DescriptionCholecystokinins precursor (CCK) [Cleaved into- - Cholecystokinin 58(CCK58); Cholecystokinin 39 (CCK39); Cholecystokinin 33 (CCK33);Cholecystokinin 12 (CCK12); Cholecystokinin 8 (CCK8)].
OrganismBos taurus
TxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Bovinae; Bos.
Subcellular LocationSecreted
Developmental StageNA
SimilarityBelongs to the gastrin/cholecystokinin family.
Tissue SpecificityNA
Post Translational ModificationThe precursor cleaved by enzymes to produce a number of active cholecystokinins.
FunctionThis peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. Binding to CCK-A receptors stimulates amylase release from the pancreas; binding to CCK-B receptors stimulates gastric acid secretion
Length115
Molecular Weight12835
NameCholecystokinin-25
SequenceVIKNLQSLDPSHRISDRDYMGWMDF
Sequence map25 (79-103)
PDB IDNA
DrugpediaNA
ReceptorP79266
DomainNA
Pharmaceutical UseNA