| Primary information |
|---|
| ID | 11434 |
| Uniprot ID | P27106 |
| Description | Muellerian-inhibiting factor precursor (MIS) (Anti-Muellerian hormone)(AMH) (Muellerian-inhibiting substance). |
| Organism | Mus musculus |
| Txonomy | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
| Subcellular Location | Secreted |
| Developmental Stage | NA |
| Similarity | Belongs to the TGF-beta family. |
| Tissue Specificity | Sertoli cells of fetal testes; and testes just after birth; but absent in adult testes. In female; AMH is expressed after birth in the granulosa cells of the follicle. AMH expression is dependent on t |
| Post Translational Modification | NA |
| Function | This glycoprotein; produced by the Sertoli cells of the testis; causes regression of the Muellerian duct. It is also able to inhibit the growth of tumors derived from tissues of Muellerian duct origin |
| Length | 555 |
| Molecular Weight | 59778 |
| Name | Muellerian-inhibiting factor |
| Sequence | NA |
| Sequence map | NA |
| PDB ID | NA |
| Drugpedia | NA |
| Receptor | Q8K592 |
| Domain | NA |
| Pharmaceutical Use | NA
|