Primary information |
---|
ID | 11429 |
Uniprot ID | P24393 |
Description | Gastrin-releasing peptide precursor (GRP) [Cleaved into- - Neuromedin-C(GRP-10)]. |
Organism | Rattus norvegicus |
Txonomy | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus. |
Subcellular Location | Secreted |
Developmental Stage | NA |
Similarity | Belongs to the bombesin/neuromedin-B/ranatensin family. |
Tissue Specificity | NA |
Post Translational Modification | NA |
Function | GRP stimulates gastrin release as well as other gastrointestinal hormones. Operates as a negative feedback regulating fear and established a causal relationship between GRP-receptor gene expression; long-term potentiation; and amygdala-dependent memory for fear |
Length | 147 |
Molecular Weight | 15817 |
Name | Gastrin-releasing peptide |
Sequence | APVSTGAGGGTVLAKMYPRGSHWAVGHLM |
Sequence map | 29 (24-52) |
PDB ID | NA |
Drugpedia | NA |
Receptor | P52500 |
Domain | NA |
Pharmaceutical Use | NA
|