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11429 details
Primary information
ID11429
Uniprot IDP24393
DescriptionGastrin-releasing peptide precursor (GRP) [Cleaved into- - Neuromedin-C(GRP-10)].
OrganismRattus norvegicus
TxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus.
Subcellular LocationSecreted
Developmental StageNA
SimilarityBelongs to the bombesin/neuromedin-B/ranatensin family.
Tissue SpecificityNA
Post Translational ModificationNA
FunctionGRP stimulates gastrin release as well as other gastrointestinal hormones. Operates as a negative feedback regulating fear and established a causal relationship between GRP-receptor gene expression; long-term potentiation; and amygdala-dependent memory for fear
Length147
Molecular Weight15817
NameGastrin-releasing peptide
SequenceAPVSTGAGGGTVLAKMYPRGSHWAVGHLM
Sequence map29 (24-52)
PDB IDNA
DrugpediaNA
ReceptorP52500
DomainNA
Pharmaceutical UseNA