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11421 details
Primary information
ID11421
Uniprot IDP19402
DescriptionCorticotropin-lipotropin precursor (Pro-opiomelanocortin) (POMC)[Cleaved into- - NPP; Melanotropin gamma (Gamma-MSH); Corticotropin(Adrenocorticotropic hormone) (ACTH); Melanotropin alpha (Alpha-MSH);Corticotropin-like intermediary peptide (CLIP); Lipotropin beta (Beta-LPH); Lipotropin gamma (Gamma-
OrganismCavia porcellus
TxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia;Hystricognathi; Caviidae; Cavia.
Subcellular LocationNA
Developmental StageNA
SimilarityBelongs to the POMC family.
Tissue SpecificityACTH and MSH are produced by the pituitary gland
Post Translational ModificationSpecific enzymatic cleavages at paired basic residues yield the different active peptides.
FunctionBeta-endorphin is an endogenous opiate
Length256
Molecular Weight28264
NameBeta-endorphin
SequenceYGGFMTSEKSQTPLVTLFKNAIVKNAHKKGQ
Sequence map31 (226-256)
PDB IDNA
DrugpediaNA
ReceptorQ9Z1S9
DomainNA
Pharmaceutical UseNA