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11418 details
Primary information
ID11418
Uniprot IDP19402
DescriptionCorticotropin-lipotropin precursor (Pro-opiomelanocortin) (POMC)[Cleaved into- - NPP; Melanotropin gamma (Gamma-MSH); Corticotropin(Adrenocorticotropic hormone) (ACTH); Melanotropin alpha (Alpha-MSH);Corticotropin-like intermediary peptide (CLIP); Lipotropin beta (Beta-LPH); Lipotropin gamma (Gamma-
OrganismCavia porcellus
TxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia;Hystricognathi; Caviidae; Cavia.
Subcellular LocationNA
Developmental StageNA
SimilarityBelongs to the POMC family.
Tissue SpecificityACTH and MSH are produced by the pituitary gland
Post Translational ModificationSpecific enzymatic cleavages at paired basic residues yield the different active peptides.
FunctionMSH (melanocyte-stimulating hormone) increases the pigmentation of skin by increasing melanin production in melanocytes
Length256
Molecular Weight28264
NameMelanotropin alpha (Alpha-MSH)
SequenceSYSMEHFRWGKPV
Sequence map13 (125-137)
PDB IDNA
DrugpediaNA
ReceptorQ9Z1S9
DomainNA
Pharmaceutical UseNA