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11391 details
Primary information
ID11391
Uniprot IDP09240
DescriptionCholecystokinins precursor (CCK) [Cleaved into- - Cholecystokinin 33(CCK33); Cholecystokinin 12 (CCK12); Cholecystokinin 8 (CCK8)].
OrganismMus musculus
TxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus.
Subcellular LocationSecreted
Developmental StageNA
SimilarityBelongs to the gastrin/cholecystokinin family.
Tissue SpecificityNA
Post Translational ModificationThe precursor cleaved by enzymes to produce a number of active cholecystokinins.
FunctionThis peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. Binding to CCK-A receptors stimulates amylase release from the pancreas; binding to CCK-B receptors stimulates gastric acid secretion
Length115
Molecular Weight12866
NameCholecystokinin-33
SequenceKAPSGRMSVLKNLQSLDPSHRISDRDYMGWMDF
Sequence map33 (71-103)
PDB IDNA
DrugpediaNA
ReceptorP56481;O08786;Q3TPL0;Q3ZB46;Q3ZB53;Q8BKF6
DomainNA
Pharmaceutical UseNA