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11374 details
Primary information
ID11374
Uniprot IDP06307
DescriptionCholecystokinins precursor (CCK) [Cleaved into- - Cholecystokinin 58(CCK58); Cholecystokinin 39 (CCK39); Cholecystokinin 33 (CCK33);Cholecystokinin 12 (CCK12); Cholecystokinin 8 (CCK8)].
OrganismHomo sapiens
TxonomyEukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea (apes); Hominidae (great apes); Homininae; Homo; Homo sapiens (Human)
Subcellular LocationSecreted
Developmental StageNA
SimilarityBelongs to the gastrin/cholecystokinin family.
Tissue SpecificityNA
Post Translational ModificationThe precursor cleaved by enzymes to produce a number of active cholecystokinins.
FunctionThis peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. Binding to CCK-A receptors stimulates amylase release from the pancreas; binding to CCK-B receptors stimulates gastric acid secretion
Length115
Molecular Weight12669
NameCholecystokinin-39
SequenceYIQQARKAPSGRMSIVKNLQNLDPSHRISDRDYMGWMDF
Sequence map39 (65-103)
PDB IDNA
DrugpediaNA
ReceptorP32238; P32239; P32238; P32239; P32238; P32238;P32239;P32238
DomainNA
Pharmaceutical UseNA