Detailed description page of Hmrbase2

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11369 details
Primary information
ID11369
Uniprot IDP04808
DescriptionProrelaxin H1 precursor [Cleaved into- - Relaxin B chain; Relaxin A chain].
OrganismHomo sapiens
TxonomyEukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea (apes); Hominidae (great apes); Homininae; Homo; Homo sapiens (Human)
Subcellular LocationSecreted
Developmental StageNA
SimilarityBelongs to the insulin family.
Tissue SpecificityProstate. Not expressed in placenta; decidua or ovary
Post Translational ModificationNA
FunctionRelaxin is an ovarian hormone that acts with estrogen to produce dilatation of the birth canal in many mammals. May be involved in remodeling of connective tissues during pregnancy; promoting growth of pubic ligaments and ripening of the cervix
Length185
Molecular Weight21146
NameRelaxin B chain
SequenceVAAKWKDDVIKLCGRELVRAQIAICGMSTWS
Sequence map31 (23-53)
PDB IDNA
DrugpediaNA
ReceptorQ9HBX9;Q8WXD0
DomainNA
Pharmaceutical UseNA