Detailed description page of Hmrbase2

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11321 details
Primary information
ID11321
Uniprot IDP01246
DescriptionSomatotropin precursor (Growth hormone).
OrganismBos taurus
TxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Bovinae; Bos.
Subcellular LocationSecreted
Developmental StageNA
SimilarityBelongs to the somatotropin/prolactin family.
Tissue SpecificityNA
Post Translational ModificationNA
FunctionPlays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues
Length217
Molecular Weight24558
NameGrowth hormone (Somatotropin) (GH)
SequenceAFPAMSLSGLFANAVLRAQHLHQLAADTFKEFERTYIPEGQRYSIQNTQVAFCFSETIPAPTGKNEAQQKSDLELLRISLLLIQSWLGPLQFLSRVFTNSLVFGTSDRVYEKLKDLEEGILALMRELEDGTPRAGQILKQTYDKFDTNMRSDDALLKNYGLLSCFRKDLHKTETYLRVMKCRRFGEASCAF
Sequence map191 (27-217)
PDB ID1BST
DrugpediaNA
ReceptorO46600
DomainNA
Pharmaceutical UseNA