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11312 details
Primary information
ID11312
Uniprot IDP01231
DescriptionLutropin subunit beta precursor (Luteinizing hormone subunit beta)(LSH-beta) (LSH-B) (LH-B) (Lutropin beta chain) (Interstitial cell-stimulating hormone) [Cleaved into- - LH beta-1; LH beta-2; LH beta-3].
OrganismOvis aries
TxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Caprinae; Ovis.
Subcellular LocationSecreted
Developmental StageNA
SimilarityBelongs to the glycoprotein hormones subunit beta family.
Tissue SpecificityNA
Post Translational ModificationNA
FunctionPromotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids. The LH alpha 3/LH beta 3 heterodimer was shown to have potent renotropic and weak gonadotropic activity
Length141
Molecular Weight15184
NameLuteinizing hormone subunit beta (LSH-B) (LH-B)(Lutropin subunit beta)
SequenceSRGPLRPLCQPINATLAAEKEACPVCITFTTSICAGYCLSMKRVLPVILPPMPQRVCTYHELRFASVRLPGCPPGVDPMVSFPVALSCHCGPCRLSSTDCGGPRTQPLACDHPPLPDILFL
Sequence map121 (21-141)
PDB IDNA
DrugpediaNA
ReceptorQ28585
DomainNA
Pharmaceutical UseNA