Detailed description page of Hmrbase2

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11297 details
Primary information
ID11297
Uniprot IDP01201
DescriptionCorticotropin-lipotropin precursor (Pro-opiomelanocortin) (POMC)[Cleaved into- - NPP; Melanotropin gamma (Gamma-MSH); Potential peptide;Corticotropin (Adrenocorticotropic hormone) (ACTH); Melanotropin alpha(Alpha-MSH); Corticotropin-like intermediary peptide (CLIP);Lipotropin beta (Beta-LPH); Lipotr
OrganismMacaca nemestrina
TxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
Subcellular LocationNA
Developmental StageNA
SimilarityBelongs to the POMC family.
Tissue SpecificityACTH and MSH are produced by the pituitary gland
Post Translational ModificationSpecific enzymatic cleavages at paired basic residues yield the different active peptides.
FunctionBeta-endorphin is an endogenous opiate
Length264
Molecular Weight29172
NameBeta-endorphin
SequenceYGGFMTSEKSQTPLVTLFKNAIIKNAYKKGQ
Sequence map31 (234-264)
PDB IDNA
DrugpediaNA
ReceptorQ864J8
DomainNA
Pharmaceutical UseNA