Detailed description page of Hmrbase2

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11295 details
Primary information
ID11295
Uniprot IDP01201
DescriptionCorticotropin-lipotropin precursor (Pro-opiomelanocortin) (POMC)[Cleaved into- - NPP; Melanotropin gamma (Gamma-MSH); Potential peptide;Corticotropin (Adrenocorticotropic hormone) (ACTH); Melanotropin alpha(Alpha-MSH); Corticotropin-like intermediary peptide (CLIP);Lipotropin beta (Beta-LPH); Lipotr
OrganismMacaca nemestrina
TxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
Subcellular LocationNA
Developmental StageNA
SimilarityBelongs to the POMC family.
Tissue SpecificityACTH and MSH are produced by the pituitary gland
Post Translational ModificationSpecific enzymatic cleavages at paired basic residues yield the different active peptides.
FunctionStimulates melanocytes to produce melanin. It performs lipid-mobilizing functions such as lipolysis and steroidogenesis.
Length264
Molecular Weight29172
NameLipotropin gamma (Gamma-LPH)
SequenceELTGQRPRAGDGPDGPADDGAGPRADLEHSLLVAAEKKDEGPYRMEHFRWGSPPKD
Sequence map56 (176-231)
PDB IDNA
DrugpediaNA
ReceptorQ864J8
DomainNA
Pharmaceutical UseNA