Detailed description page of Hmrbase2

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11292 details
Primary information
ID11292
Uniprot IDP01201
DescriptionCorticotropin-lipotropin precursor (Pro-opiomelanocortin) (POMC)[Cleaved into- - NPP; Melanotropin gamma (Gamma-MSH); Potential peptide;Corticotropin (Adrenocorticotropic hormone) (ACTH); Melanotropin alpha(Alpha-MSH); Corticotropin-like intermediary peptide (CLIP);Lipotropin beta (Beta-LPH); Lipotr
OrganismMacaca nemestrina
TxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
Subcellular LocationNA
Developmental StageNA
SimilarityBelongs to the POMC family.
Tissue SpecificityACTH and MSH are produced by the pituitary gland
Post Translational ModificationSpecific enzymatic cleavages at paired basic residues yield the different active peptides.
FunctionACTH stimulates the adrenal glands to release cortisol
Length264
Molecular Weight29172
NameCorticotropin
SequenceSYSMEHFRWGKPVGKKRRPVKVYPNGAEDESAEAFPLEF
Sequence map39 (135-173)
PDB IDNA
DrugpediaNA
ReceptorQ864J8
DomainNA
Pharmaceutical UseNA