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11289 details
Primary information
ID11289
Uniprot IDP01193
DescriptionCorticotropin-lipotropin precursor (Pro-opiomelanocortin) (POMC)[Cleaved into- - NPP; Melanotropin gamma (Gamma-MSH); Corticotropin(Adrenocorticotropic hormone) (ACTH); Melanotropin alpha (Alpha-MSH);Corticotropin-like intermediary peptide (CLIP); Lipotropin beta (Beta-LPH); Lipotropin gamma (Gamma-
OrganismMus musculus
TxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus.
Subcellular LocationNA
Developmental StageNA
SimilarityBelongs to the POMC family.
Tissue SpecificityACTH and MSH are produced by the pituitary gland
Post Translational ModificationSpecific enzymatic cleavages at paired basic residues yield the different active peptides.
FunctionBeta-endorphin is an endogenous opiate
Length235
Molecular Weight26707
NameBeta-endorphin
SequenceYGGFMTSEKSQTPLVTLFKNAIIKNAHKKGQ
Sequence map31 (205-235)
PDB IDNA
DrugpediaNA
ReceptorQ64326;Q01727
DomainNA
Pharmaceutical UseNA