Detailed description page of Hmrbase2

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11275 details
Primary information
ID11275
Uniprot IDP01192
DescriptionCorticotropin-lipotropin precursor (Pro-opiomelanocortin) (POMC)[Cleaved into- - NPP; Melanotropin gamma (Gamma-MSH); Corticotropin(Adrenocorticotropic hormone) (ACTH); Melanotropin alpha (Alpha-MSH);Corticotropin-like intermediary peptide (CLIP); Lipotropin beta (Beta-LPH); Lipotropin gamma (Gamma-
OrganismSus scrofa
TxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus.
Subcellular LocationNA
Developmental StageNA
SimilarityBelongs to the POMC family.
Tissue SpecificityACTH and MSH are produced by the pituitary gland
Post Translational ModificationSpecific enzymatic cleavages at paired basic residues yield the different active peptides.
FunctionACTH stimulates the adrenal glands to release cortisol
Length267
Molecular Weight28895
NameCorticotropin
SequenceSYSMEHFRWGKPVGKKRRPVKVYPNGAEDELAEAFPLEF
Sequence map39 (136-174)
PDB IDNA
DrugpediaNA
ReceptorQ9TU05
DomainNA
Pharmaceutical UseNA