Detailed description page of Hmrbase2

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11272 details
Primary information
ID11272
Uniprot IDP01191
DescriptionCorticotropin-lipotropin precursor (Pro-opiomelanocortin) (POMC)[Cleaved into- - NPP; Melanotropin gamma (Gamma-MSH); Corticotropin(Adrenocorticotropic hormone) (ACTH); Melanotropin alpha (Alpha-MSH);Corticotropin-like intermediary peptide (CLIP); Lipotropin beta (Beta-LPH); Lipotropin gamma (Gamma-
OrganismOvis aries
TxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Caprinae; Ovis.
Subcellular LocationNA
Developmental StageNA
SimilarityBelongs to the POMC family.
Tissue SpecificityACTH and MSH are produced by the pituitary gland
Post Translational ModificationSpecific enzymatic cleavages at paired basic residues yield the different active peptides.
FunctionBeta-endorphin is an endogenous opiate
Length212
Molecular Weight23464
NameBeta-endorphin
SequenceYGGFMTSEKSQTPLVTLFKNAIIKNAHKKGQ
Sequence map31 (182-212)
PDB IDNA
DrugpediaNA
ReceptorQ9TU77;O19037
DomainNA
Pharmaceutical UseNA