Detailed description page of Hmrbase2

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11260 details
Primary information
ID11260
Uniprot IDP01190
DescriptionCorticotropin-lipotropin precursor (Pro-opiomelanocortin) (POMC)[Cleaved into- - NPP; Melanotropin gamma (Gamma-MSH); Corticotropin(Adrenocorticotropic hormone) (ACTH); Melanotropin alpha (Alpha-MSH);Corticotropin-like intermediary peptide (CLIP); Lipotropin beta (Beta-LPH); Lipotropin gamma (Gamma-
OrganismBos taurus
TxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Bovinae; Bos.
Subcellular LocationNA
Developmental StageNA
SimilarityBelongs to the POMC family.
Tissue SpecificityACTH and MSH are produced by the pituitary gland
Post Translational ModificationSpecific enzymatic cleavages at paired basic residues yield the different active peptides.
FunctionACTH stimulates the adrenal glands to release cortisol
Length265
Molecular Weight29260
NameCorticotropin
SequenceSYSMEHFRWGKPVGKKRRPVKVYPNGAEDESAQAFPLEF
Sequence map39 (132-170)
PDB IDNA
DrugpediaNA
ReceptorP47798
DomainNA
Pharmaceutical UseNA