| Primary information |
|---|
| ID | 11243 |
| Uniprot ID | P01148 |
| Description | Progonadoliberin-1 precursor (Progonadoliberin I) [Cleaved into- -Gonadoliberin-1 (Gonadoliberin I) (Luteinizing hormone-releasinghormone I) (LH-RH I) (Gonadotropin-releasing hormone I) (GnRH-I)(Luliberin I) (Gonadorelin); GnRH-associated peptide 1 (GnRH-associated peptide I)]. |
| Organism | Homo sapiens |
| Txonomy | Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea (apes); Hominidae (great apes); Homininae; Homo; Homo sapiens (Human) |
| Subcellular Location | Secreted |
| Developmental Stage | NA |
| Similarity | Belongs to the GnRH family. |
| Tissue Specificity | NA |
| Post Translational Modification | NA |
| Function | Stimulates the secretion of gonadotropins; it stimulates the secretion of both luteinizing and follicle-stimulating hormones |
| Length | 92 |
| Molecular Weight | 10380 |
| Name | Gonadoliberin-1 |
| Sequence | QHWSYGLRPG |
| Sequence map | 10 (24-33) |
| PDB ID | NA |
| Drugpedia | NA |
| Receptor | P30968;P30968 |
| Domain | NA |
| Pharmaceutical Use | Available under the names Factrel (Ayerst Labs); Lutrepulse or Lutrelef (Ferring Pharmaceuticals) and Relisorm (Serono). Used in evaluating hypothalamic-pituitary gonadotropic function.
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