Detailed description page of Hmrbase2

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11235 details
Primary information
ID11235
Uniprot IDO43555
DescriptionProgonadoliberin-2 precursor (Progonadoliberin II) [Cleaved into- -Gonadoliberin-2 (Gonadoliberin II) (Luteinizing hormone-releasinghormone II) (LH-RH II) (Gonadotropin-releasing hormone II) (GnRH II)(Luliberin II); GnRH-associated peptide 2 (GnRH-associated peptideII)].
OrganismHomo sapiens
TxonomyEukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea (apes); Hominidae (great apes); Homininae; Homo; Homo sapiens (Human)
Subcellular LocationSecreted
Developmental StageNA
SimilarityBelongs to the GnRH family.
Tissue SpecificityMidbrain; expressed at significantly higher levels outside the brain (up to 30-fold); particularly in the kidney; bone marrow and prostate
Post Translational ModificationNA
FunctionStimulates the secretion of gonadotropins; it stimulates the secretion of both luteinizing and follicle-stimulating hormones
Length120
Molecular Weight12918
NameGonadoliberin-2
SequenceQHWSHGWYPG
Sequence map10 (24-33)
PDB IDNA
DrugpediaNA
ReceptorQ96P88;P30968;Q96P88
DomainNA
Pharmaceutical UseNA