Detailed description page of Hmrbase2

This page displays user query in tabular form.

11167 details
Primary information
ID11167
Uniprot IDO93464
DescriptionCholecystokinins precursor (CCK8) [Cleaved into- - Cholecystokinin 8 (CCK8);Cholecystokinin 12 (CCK12); Cholecystokinin 26 (CCK26);Cholecystokinin 36 (CCK36); Cholecystokinin 69 (CCK69)].
OrganismCarassius auratus
TxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;Cyprinidae; Carassius.
Subcellular LocationSecreted (Potential)
Developmental StageExpression in the brain shows variation throughout the seasonal sexual cycle; in the optic tectum-thalamus of females; expression levels are lower in early gonadal recrudescence (October) compared to
SimilarityBelongs to the gastrin/cholecystokinin family.
Tissue SpecificityExpressed in the ovary; kidney; gill; gastrointestinal tract and pituitary. Differentially expressed in the brain in the optic tectum-thalamus; hypothalamus; telencephalon; olfactory bulb and tract; p
Post Translational ModificationThe precursor is cleaved by enzymes to produce a number of active cholecystokinins.
FunctionThis peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Induces the secretion of gonadotropin and growth hormone from the pituitary. Suppresses food intake and decreases the expression of preprosomatostatin genes in the forebrain
Length123
Molecular Weight13439
NameCholecystokinin 26
SequenceSPSPKSKSMGNNHRIKDRDYLGWMDF
Sequence map26 (86-111)
PDB IDNA
DrugpediaNA
ReceptorNA
DomainNA
Pharmaceutical UseNA