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11159 details
Primary information
ID11159
Uniprot IDP47851
DescriptionGastrin-releasing peptide precursor (GRP) [Cleaved into- - Neuromedin-C(GRP-10)].
OrganismOvis aries
TxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Caprinae; Ovis.
Subcellular LocationSecreted
Developmental StageNA
SimilarityBelongs to the bombesin/neuromedin-B/ranatensin family.
Tissue SpecificityNA
Post Translational ModificationNA
FunctionGRP stimulates gastrin release as well as other gastrointestinal hormones. Operates as a negative feedback regulating fear and established a causal relationship between GRP-receptor gene expression; long-term potentiation; and amygdala-dependent memory for fear
Length134
Molecular Weight14855
NameGastrin-releasing peptide
SequenceAPVTAGRAGALAKMYTRGNHWAVGHLM
Sequence map27 (24-50)
PDB IDNA
DrugpediaNA
ReceptorNA
DomainNA
Pharmaceutical UseNA