Detailed description page of Hmrbase2

This page displays user query in tabular form.

11094 details
Primary information
ID11094
Uniprot IDP68259
DescriptionGlucagon precursor [Cleaved into- - Glicentin-related polypeptide (GRPP);Glucagon; Glucagon-like peptide 1 (GLP-1); Glucagon-like peptide 1(7-37) (GLP-1(7-37)); Glucagon-like peptide 1(7-36) (GLP-1(7-36));Glucagon-like peptide 2 (GLP-2)].
OrganismGallus gallus
TxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves;Neognathae; Galliformes; Phasianidae; Phasianinae; Gallus.
Subcellular LocationSecreted
Developmental StageNA
SimilarityBelongs to the glucagon family.
Tissue SpecificityNA
Post Translational ModificationProglucagon is posttranslationally processed in a tissue- specific manner in pancreatic A cells and intestinal L cells. In pancreatic A cells; the major bioactive hormone is glucagon cleaved by PCSK2/
FunctionGLP-2 stimulates intestinal growth and up-regulates villus height in the small intestine; concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis
Length206
Molecular Weight23876
NameGlucagon-like peptide 2
SequenceHADGTFTSDINKILDDMAAKEFLKWLINTKVTQ
Sequence map33 (166-198)
PDB IDNA
DrugpediaNA
ReceptorNA
DomainNA
Pharmaceutical UseNA