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11028 details
Primary information
ID11028
Uniprot IDP01263
DescriptionCalcitonin-1 precursor.
OrganismOncorhynchus keta
TxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei;Protacanthopterygii; Salmoniformes; Salmonidae; Oncorhynchus.
Subcellular LocationSecreted
Developmental StageNA
SimilarityBelongs to the calcitonin family.
Tissue SpecificityNA
Post Translational ModificationNA
FunctionCauses a rapid but short-lived drop in the level of calcium and phosphate in blood by promoting the incorporation of those ions in the bones
Length136
Molecular Weight15179
NameCalcitonin-1
SequenceCSNLSTCVLGKLSQELHKLQTYPRTNTGSGTP
Sequence map32 (83-114)
PDB ID2GLG2GLH
DrugpediaNA
ReceptorNA
DomainNA
Pharmaceutical UseAvailable under the names Calcimar (Rhone-Poulenc Rorer); Miacalcin (Novartis) or Forcaltonin (Unigene). Used for the treatment of Paget's disease and hypercalcemia in malignancy.