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10723 details
Primary information
ID10723
Uniprot IDO18938
DescriptionSomatotropin precursor (Growth hormone).
OrganismBubalus bubalis
TxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Bovinae; Bubalus.
Subcellular LocationSecreted
Developmental StageNA
SimilarityBelongs to the somatotropin/prolactin family.
Tissue SpecificityNA
Post Translational ModificationNA
FunctionPlays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues
Length217
Molecular Weight24618
NameSomatotropin
SequenceAFPAMSLSSLFANAVLWAQHLHQLAADTFKEFERTYIPEGQRYSIQNTQVAFCFSETIPAPTGKNEAQQKSDLELLRISLLLIQSWLGPLQFLSRVFTNSLVFGTSDRVYEKLKDLEEGILALMRELEDGTPRAGQILKQTYDKFDTNMRSDDALLKNYGLLSCFRKDLHKTETYLRVMKCRRFGEASCAF
Sequence map 191 (27-217)
PDB IDNA
DrugpediaNA
ReceptorNA
DomainNA
Pharmaceutical UseNA