Detailed description page of Hmrbase2

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10710 details
Primary information
ID10710
Uniprot IDP58757
DescriptionGrowth hormone variant precursor (GH-V) (Placenta-specific growthhormone) (Growth hormone 2).
OrganismPan troglodytes
TxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Pan.
Subcellular LocationSecreted
Developmental StageNA
SimilarityBelongs to the somatotropin/prolactin family.
Tissue SpecificityExpressed in the placenta
Post Translational ModificationNA
FunctionPlays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues
Length217
Molecular Weight24991
NameGrowth hormone variant
SequenceFPTIPLSRLFDNAMLRAHRLYQLAYDTYQEFEEAYILKEQKYSFLQNPQTSLCFSESIPTPSNRVKTQQKSNLELLRISLLLIQSWLEPVQLLRSVFANSLVYGASDSNVYRHLKDLEEGIQTLMWRLEDGSPRTGQIFNQSYSKFDTKSHNDDALLKNYGLLYCFRKDMDKVETFLRIVQCRSVEGSCGF
Sequence map191 (27-217)
PDB IDNA
DrugpediaNA
ReceptorNA
DomainNA
Pharmaceutical UseNA