Detailed description page of Hmrbase2

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10709 details
Primary information
ID10709
Uniprot IDQ07370
DescriptionGrowth hormone variant precursor (GH-V) (Placenta-specific growthhormone) (Growth hormone 2).
OrganismMacaca mulatta
TxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
Subcellular LocationSecreted
Developmental StageNA
SimilarityBelongs to the somatotropin/prolactin family.
Tissue SpecificityExpressed in the placenta
Post Translational ModificationNA
FunctionPlays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues
Length217
Molecular Weight25221
NameGrowth hormone variant
SequenceFPTIPLSWLFNTAVFRAHHLHKLAFDTYPKLEEAYIPKEQKYSFLRNPQTSLCFSESIPTPSNKEETQQKSNLELLHISLLLIQSWLEPVQFLRSVFANHLVHTNSNFDIYLYLKKLEEGIQTLMERLEDGSPRTGQIFKETYSKYDTNSHNDDTLLKNYRLLYCFRKDMNKVETFLRTVRCRAVEGSCGF
Sequence map191 (27-217)
PDB IDNA
DrugpediaNA
ReceptorNA
DomainNA
Pharmaceutical UseNA