Primary information |
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ID | 10613 |
Uniprot ID | A0MLS4 |
Description | Appetite-regulating hormone precursor (Growth hormone secretagogue)(Growth hormone-releasing peptide) (Motilin-related peptide)[Cleaved into- - Ghrelin; Obestatin]. |
Organism | Papio hamadryas |
Txonomy | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Cercopithecidae; Cercopithecinae; Papio. |
Subcellular Location | Secreted |
Developmental Stage | NA |
Similarity | Belongs to the motilin family. |
Tissue Specificity | NA |
Post Translational Modification | O-n-octanoylation is essential for ghrelin activity. Amidation of Leu-98 is essential for obestatin activity. |
Function | Ghrelin is the ligand for growth hormone secretagogue receptor type 1 (GHSR). Induces the release of growth hormone from the pituitary. Has an appetite-stimulating effect; induces adiposity and stimulates gastric acid secretion. Involved in growth regulation |
Length | 117 |
Molecular Weight | 12913 |
Name | Ghrelin |
Sequence | GSSFLSPEHQRAQQRKESKKPPAKLQPR |
Sequence map | 28 (24-51) |
PDB ID | NA |
Drugpedia | NA |
Receptor | NA |
Domain | NA |
Pharmaceutical Use | NA
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