Detailed description page of Hmrbase2

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10502 details
Primary information
ID10502
Uniprot IDP69156
DescriptionPro-MCH 2 precursor [Cleaved into- - Neuropeptide-glutamic acid-valine (NEV)(Neuropeptide E-V); Melanin-concentrating hormone (MCH)].
OrganismOncorhynchus tschawytscha
TxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei;Protacanthopterygii; Salmoniformes; Salmonidae; Oncorhynchus.
Subcellular LocationNA
Developmental StageNA
SimilarityBelongs to the melanin-concentrating hormone family.
Tissue SpecificityPituitary gland. Produced in neurons of lateral basal hypothalamus which project both to the brain and to the neural lobe of the pituitary gland from where MCH is released
Post Translational ModificationNA
FunctionPlays a role in skin pigmentation by antagonizing the action of melanotropin alpha. Induces melanin concentration within the melanophores. May participate in the control of the hypothalamo-pituitary adrenal gland axis by inhibiting the release of ACTH
Length132
Molecular Weight14710
NameMelanin-concentrating hormone
SequenceDTMRCMVGRVYRPCWEV
Sequence map17 (116-132)
PDB IDNA
DrugpediaNA
ReceptorNA
DomainNA
Pharmaceutical UseNA