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10476 details
Primary information
ID10476
Uniprot IDP63152
DescriptionGastrin-releasing peptide (GRP) [Cleaved into- - Neuromedin-C (GRP-10)].
OrganismCavia porcellus
TxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia;Hystricognathi; Caviidae; Cavia.
Subcellular LocationSecreted
Developmental StageNA
SimilarityBelongs to the bombesin/neuromedin-B/ranatensin family.
Tissue SpecificityNA
Post Translational ModificationNA
FunctionGRP stimulates gastrin release as well as other gastrointestinal hormones. Operates as a negative feedback regulating fear and established a causal relationship between GRP-receptor gene expression; long-term potentiation; and amygdala-dependent memory for fear
Length27
Molecular Weight2806
NameGastrin-releasing peptide
SequenceAPVSVGGGTVLAKMYPRGNHWAVGHLM
Sequence map27 (1-27)
PDB IDNA
DrugpediaNA
ReceptorNA
DomainNA
Pharmaceutical UseNA