| Primary information |
|---|
| ID | 10447 |
| Uniprot ID | P19713 |
| Description | Pro-MCH 1 precursor [Cleaved into- - Neuropeptide-glutamic acid-valine (NEV)(Neuropeptide E-V); Melanin-concentrating hormone (MCH)]. |
| Organism | Oncorhynchus keta |
| Txonomy | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei;Protacanthopterygii; Salmoniformes; Salmonidae; Oncorhynchus. |
| Subcellular Location | NA |
| Developmental Stage | NA |
| Similarity | Belongs to the melanin-concentrating hormone family. |
| Tissue Specificity | Pituitary gland. Produced in neurons of lateral basal hypothalamus which project both to the brain and to the neural lobe of the pituitary gland from where MCH is released |
| Post Translational Modification | NA |
| Function | Plays a role in skin pigmentation by antagonizing the action of melanotropin alpha. Induces melanin concentration within the melanophores. May participate in the control of the hypothalamo-pituitary adrenal gland axis by inhibiting the release of ACTH |
| Length | 132 |
| Molecular Weight | 14682 |
| Name | Melanin-concentrating hormone |
| Sequence | DTMRCMVGRVYRPCWEV |
| Sequence map | 17 (116-132) |
| PDB ID | NA |
| Drugpedia | NA |
| Receptor | NA |
| Domain | NA |
| Pharmaceutical Use | NA
|