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10361 details
Primary information
ID10361
Uniprot IDQ9PU41
DescriptionCholecystokinins precursor (CCK) [Cleaved into- - Cholecystokinin 70(CCK70); Cholecystokinin 8 (CCK8); Cholecystokinin 7 (CCK7)].
OrganismGallus gallus
TxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves;Neognathae; Galliformes; Phasianidae; Phasianinae; Gallus.
Subcellular LocationSecreted
Developmental StageNA
SimilarityBelongs to the gastrin/cholecystokinin family.
Tissue SpecificityIn the small intestine; the major production site is around the vitelline diverticulum
Post Translational ModificationThe precursor is cleaved by enzymes to produce a number of active cholecystokinins.
FunctionThis peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. It also decreases food intake and regulates gastrointestinal physiological processes.
Length130
Molecular Weight14091
NameCholecystokinin-8
SequenceDYMGWMDF
Sequence map8 (111-118)
PDB IDNA
DrugpediaNA
ReceptorQ7T1P8
DomainNA
Pharmaceutical UseNA