Detailed description page of Hmrbase2

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10352 details
Primary information
ID10352
Uniprot IDQ9GKY5
DescriptionAppetite-regulating hormone precursor (Growth hormone secretagogue)(Growth hormone-releasing peptide) (Motilin-related peptide)[Cleaved into- - Ghrelin; Obestatin].
OrganismSus scrofa
TxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus.
Subcellular LocationSecreted
Developmental StageNA
SimilarityBelongs to the motilin family.
Tissue SpecificityNA
Post Translational ModificationO-n-octanoylation is essential for ghrelin activity. Amidation of Leu-99 is essential for obestatin activity.
FunctionObestatin may be the ligand for GPR39. May have an appetite-reducing effect resulting in decreased food intake. May reduce gastric emptying activity and jejunal motility
Length118
Molecular Weight12786
NameObestatin
SequenceFNAPCDVGIKLSGAQSDQHGQPL
Sequence map23 (77-99)
PDB IDNA
DrugpediaNA
ReceptorP34999
DomainNA
Pharmaceutical UseNA