Primary information |
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ID | 10348 |
Uniprot ID | Q9BDJ6 |
Description | Appetite-regulating hormone precursor (Growth hormone secretagogue)(Growth hormone-releasing peptide) (Motilin-related peptide)[Cleaved into- - Ghrelin; Obestatin]. |
Organism | Bos taurus |
Txonomy | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Bovinae; Bos. |
Subcellular Location | Secreted |
Developmental Stage | NA |
Similarity | Belongs to the motilin family. |
Tissue Specificity | NA |
Post Translational Modification | O-n-octanoylation is essential for ghrelin activity. Amidation of Leu-97 is essential for obestatin activity. |
Function | Obestatin may be the ligand for GPR39. May have an appetite-reducing effect resulting in decreased food intake. May reduce gastric emptying activity and jejunal motility |
Length | 116 |
Molecular Weight | 12793 |
Name | Obestatin |
Sequence | FNAPFNIGIKLAGAQSLQHGQTL |
Sequence map | 23 (75-97) |
PDB ID | NA |
Drugpedia | NA |
Receptor | Q9BDH9;Q9N1F8;Q9TUJ0;Q9TUJ1 |
Domain | NA |
Pharmaceutical Use | NA
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