Detailed description page of Hmrbase2

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10345 details
Primary information
ID10345
Uniprot IDQ96T91
DescriptionGlycoprotein hormone alpha-2 precursor (Thyrostimulin subunit alpha).
OrganismHomo sapiens
TxonomyEukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea (apes); Hominidae (great apes); Homininae; Homo; Homo sapiens (Human)
Subcellular LocationSecreted
Developmental StageNA
SimilarityBelongs to the glycoprotein hormones subunit alpha family.
Tissue SpecificityFound in a variety of tissues
Post Translational ModificationGlycosylated.
FunctionStimulates the thyroid. Binds and activates THSR; leads to increased cAMP production
Length129
Molecular Weight14163
NameGlycoprotein hormone alpha-2
SequenceQEAVIPGCHLHPFNVTVRSDRQGTCQGSHVAQACVGHCESSAFPSRYSVLVASGYRHNITSVSQCCTISGLKKVKVQLQCVGSRREELEIFTARACQCDMCRLSRY
Sequence map106 (24-129)
PDB IDNA
DrugpediaNA
ReceptorP16473
DomainNA
Pharmaceutical UseNA