| Primary information |
|---|
| ID | 10326 |
| Uniprot ID | Q5XXR2 |
| Description | Pro-MCH precursor [Cleaved into- - Neuropeptide-glycine-glutamic acid (NGE)(Neuropeptide G-E); Neuropeptide-glutamic acid-isoleucine (NEI)(Neuropeptide E-I); Melanin-concentrating hormone (MCH)]. |
| Organism | Canis familiaris |
| Txonomy | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae;Canis. |
| Subcellular Location | Secreted |
| Developmental Stage | NA |
| Similarity | Belongs to the melanin-concentrating hormone family. |
| Tissue Specificity | NA |
| Post Translational Modification | Pro-MCH is processed differentially in the brain and in peripheral organs producing two neuropeptides; NEI and MCH. A third peptide; NGE; may also be produced. Preferential processing in neurons by pr |
| Function | MCH may act as a neurotransmitter or neuromodulator in a broad array of neuronal functions directed toward the regulation of goal-directed behavior; such as food intake; and general arousal |
| Length | 165 |
| Molecular Weight | 18644 |
| Name | Melanin-concentrating hormone |
| Sequence | DFDMLRCMLGRVYRPCWQV |
| Sequence map | 19 (147-165) |
| PDB ID | NA |
| Drugpedia | NA |
| Receptor | Q8MIP5;Q8MIP6 |
| Domain | NA |
| Pharmaceutical Use | NA
|