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10316 details
Primary information
ID10316
Uniprot IDQ04618
DescriptionCorticotropin-lipotropin B precursor (Pro-opiomelanocortin B) (POMC B)[Cleaved into- - NPP 2; Corticotropin (Adrenocorticotropic hormone) (ACTH);Melanotropin alpha 2 (Alpha-MSH 2); Corticotropin-like intermediarypeptide 2 (CLIP-2); Lipotropin beta (Beta-LPH); Lipotropin gamma(Gamma-LPH); Melanotropi
OrganismOncorhynchus mykiss
TxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei;Protacanthopterygii; Salmoniformes; Salmonidae; Oncorhynchus.
Subcellular LocationNA
Developmental StageExpressed only in sexually active fish.
SimilarityBelongs to the POMC family.
Tissue SpecificityPituitary and hypothalamus of adult diploid animals
Post Translational ModificationSpecific enzymatic cleavages at paired basic residues yield the different active peptides. Acetylation of beta-endorphin occurs in a tissue-specific manner.
FunctionNA
Length240
Molecular Weight26719
NameLipotropin beta (Beta-LPH)
SequenceQLSSWEDEMVGALGNQGAKAQTKVVPRTLTVTGLQDKKDGSYRMGHFRWGSPTAIKRYGGFMKPYTQQSHKPLITLLKHVTLKNEQ
Sequence map86 (155-240)
PDB IDNA
DrugpediaNA
ReceptorQ6QLQ0;Q6QLQ1
DomainNA
Pharmaceutical UseNA