Detailed description page of Hmrbase2

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10307 details
Primary information
ID10307
Uniprot IDP81278
DescriptionProlactin-releasing peptide precursor (PrRP) (Prolactin-releasinghormone) [Cleaved into- - Prolactin-releasing peptide PrRP31; Prolactin-releasing peptide PrRP20].
OrganismRattus norvegicus
TxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus.
Subcellular LocationSecreted
Developmental StageNA
SimilarityNA
Tissue SpecificityWidely expressed; with highest levels in medulla oblongata and hypothalamus
Post Translational ModificationNA
FunctionStimulates prolactin (PRL) release and regulates the expression of prolactin through its receptor GPR10. May stimulate lactotrophs directly to secrete PRL
Length83
Molecular Weight9215
NameProlactin-releasing peptide PrRP20
SequenceTPDINPAWYTGRGIRPVGRF
Sequence map20 (33-52)
PDB IDNA
DrugpediaNA
ReceptorQ64121
DomainNA
Pharmaceutical UseNA