Primary information |
---|
ID | 10109 |
Uniprot ID | Q9BEF8 |
Description | Appetite-regulating hormone precursor (Growth hormone secretagogue)(Growth hormone-releasing peptide) (Motilin-related peptide)[Cleaved into- - Ghrelin; Obestatin]. |
Organism | Canis familiaris |
Txonomy | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae;Canis. |
Subcellular Location | Secreted |
Developmental Stage | NA |
Similarity | Belongs to the motilin family. |
Tissue Specificity | NA |
Post Translational Modification | O-n-octanoylation is essential for ghrelin activity. Amidation of Leu-98 is essential for obestatin activity. |
Function | Obestatin may be the ligand for GPR39. May have an appetite-reducing effect resulting in decreased food intake. May reduce gastric emptying activity and jejunal motility |
Length | 117 |
Molecular Weight | 13007 |
Name | Obestatin |
Sequence | FNAPFDVGIKLSGPQYHQHGQAL |
Sequence map | 23 (76-98) |
PDB ID | NA |
Drugpedia | NA |
Receptor | NA |
Domain | NA |
Pharmaceutical Use | NA
|