Primary information |
---|
ID | 10108 |
Uniprot ID | Q9BEF8 |
Description | Appetite-regulating hormone precursor (Growth hormone secretagogue)(Growth hormone-releasing peptide) (Motilin-related peptide)[Cleaved into- - Ghrelin; Obestatin]. |
Organism | Canis familiaris |
Txonomy | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae;Canis. |
Subcellular Location | Secreted |
Developmental Stage | NA |
Similarity | Belongs to the motilin family. |
Tissue Specificity | NA |
Post Translational Modification | O-n-octanoylation is essential for ghrelin activity. Amidation of Leu-98 is essential for obestatin activity. |
Function | Ghrelin is the ligand for growth hormone secretagogue receptor type 1 (GHSR). Induces the release of growth hormone from the pituitary. Has an appetite-stimulating effect; induces adiposity and stimulates gastric acid secretion. Involved in growth regulation |
Length | 117 |
Molecular Weight | 13007 |
Name | Ghrelin |
Sequence | GSSFLSPEHQKLQQRKESKKPPAKLQPR |
Sequence map | 28 (24-51) |
PDB ID | NA |
Drugpedia | NA |
Receptor | NA |
Domain | NA |
Pharmaceutical Use | NA
|