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10098 details
Primary information
ID10098
Uniprot IDQ25154
DescriptionCrustacean hyperglycemic hormones isoform B precursor [Cleaved into- - CHHprecursor-related peptide B (CPRP-B); Crustacean hyperglycemic hormoneB (CHH-B)].
OrganismHomarus americanus
TxonomyEukaryota; Metazoa; Arthropoda; Crustacea; Malacostraca;Eumalacostraca; Eucarida; Decapoda; Pleocyemata; Astacidea;Nephropoidea; Nephropidae; Homarus.
Subcellular LocationSecreted
Developmental StageNA
SimilarityBelongs to the arthropod CHH/MIH/GIH/VIH hormone family.
Tissue SpecificityProduced by the medulla terminalis X-organ in the eyestalks and transported to the sinus gland where they are stored and released. Present also in the ventral nervous system
Post Translational ModificationStereoinversion of L-Phe (form CHH-B-I) to D-Phe (form CHH-B- II).
FunctionHormone found in the sinus gland of isopods and decapods which controls the blood sugar level. Has a secretagogue action over the amylase released from the midgut gland. May act as a stress hormone and may be involved in the control of molting and reproduction
Length134
Molecular Weight15050
NameCrustacean hyperglycemic hormone B
SequenceQVFDQACKGVYDRNLFKKLNRVCEDCYNLYRKPFIVTTCRENCYSNRVFRQCLDDLLLSDVIDEYVSNVQMV
Sequence map72 (61-132)
PDB IDNA
DrugpediaNA
ReceptorNA
DomainNA
Pharmaceutical UseNA