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10043 details
Primary information
ID10043
Uniprot IDP82965
DescriptionAntidiuretic factor A (ADFa) (ADF) (Antidiuretic hormone A) (ADHA).
OrganismTenebrio molitor
TxonomyEukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Coleoptera; Polyphaga; Cucujiformia;Tenebrionidae; Tenebrio.
Subcellular LocationSecreted
Developmental StageNA
SimilarityTo T.molitor cuticular protein LPCP29 C-terminal region.
Tissue SpecificityNA
Post Translational ModificationNA
FunctionStrong inhibitor of fluid secretion by the Malpighian tubules. Uses cGMP as a second messenger and inhibits fluid production by decreasing cAMP concentration. Reduces isosmotic fluid secretion by inhibiting electroneutral and non-conductive transport pathways. Reverses the stimulatory effect of diuretic hormone I
Length14
Molecular Weight1543
NameAntidiuretic factor A
SequenceVVNTPGHAVSYHVY
Sequence map14 (1-14)
PDB IDNA
DrugpediaNA
ReceptorNA
DomainNA
Pharmaceutical UseNA