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20653 details
Primary information
ID20653
Pubchem IDNA
NameMitotane
DescriptionMitotane is only found in individuals that have used or taken this drug. It is a derivative of the insecticide dichlorodiphenyldichloroethane that specifically inhibits cells of the adrenal cortex and their production of hormones. It is used to treat adrenocortical tumors and causes CNS damage; but
SynonymLysodren;Bristol myers squibb brand OF mitotane;Khloditan;ortho;Para-DDD;Chloditan;Bristol-myers squibb brand OF mitotane;O;P-DDD;ortho;Para DDD;Chlodithane;Mytotan;Lysodren;Bristol myers squibb brand
Molecular Weight320.041
FormulaC14H10Cl4
IUPAC1-chloro-4-[2;2-dichloro-1-(2-chlorophenyl)ethyl]benzene
SMILEClC(Cl)C(C1=CC=C(Cl)C=C1)C1=CC=CC=C1Cl
PDB IDNA
KEGGNA
HMDB IDHMDB0014786
Melting Point (Degree C)77
Water Solubility9.4e-06 g/L
Drugbank IDNA
ReceptorNA
ReferenceHMDB