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20081 details
Primary information
ID20081
Pubchem ID5754
NameHydrocortisone
DescriptionThe main glucocorticoid secreted by the ADRENAL CORTEX. Its synthetic counterpart is used; either as an injection or topically; in the treatment of inflammation; allergy; collagen diseases; asthma; adrenocortical deficiency; shock; and some neoplastic conditions.
SynonymHydrocortisone Cortisol Cortef Acticort Cetacort Hytone Dihydrocostisone Hydrocortisyl Hydrocortone Corticreme
Molecular Weight362.46
FormulaC21H30O5
IUPAC(8S;9S;10R;11S;13S;14S;17R)-11;17-dihydroxy-17-(2-hydroxyacetyl)-10;13-dimethyl-2;6;7;8;9;11;12;14;15;16-decahydro-1H-cyclopenta[a]phenanthren-3-one
SMILECC12CCC(=O)C=C1CCC3C2C(CC4(C3CCC4(C(=O)CO)O)C)O
PDB ID2Q1V;2V95;2VDY
KEGGC00735; D00088
HMDB IDHMDB0000063
Melting Point (Degree C)220
Water Solubility320mg/ml at 25C
Drugbank IDDB00741
ReceptorP04150
ReferencePubchem; HMDB