| Primary information |
|---|
| ID | 20029 |
| Pubchem ID | 32798 |
| Name | Clobetasol propionate |
| Description | A derivative of PREDNISOLONE with high glucocorticoid activity and low mineralocorticoid activity. Absorbed through the skin faster than FLUOCINONIDE; it is used topically in treatment of PSORIASIS but may cause marked adrenocortical suppression. |
| Synonym | Clobex Clobetasol Clobesol Dermovate Temovate Cormax Luxiq Temovate E Embeline Olux |
| Molecular Weight | 466.97 |
| Formula | C25H32ClFO5 |
| IUPAC | [(8S;9R;10S;11S;13S;14S;16S;17R)-17-(2-chloroacetyl)-9-fluoro-11-hydroxy-10;13;16-trimethyl-3-oxo-6;7;8;11;12;14;15;16-octahydrocyclopenta[a]phenanthren-17-yl] propanoate |
| SMILE | CCC(=O)OC1(C(CC2C1(CC(C3(C2CCC4=CC(=O)C=CC43C)F)O)C)C)C(=O)CCl |
| PDB ID | NA |
| KEGG | D01272 |
| HMDB ID | NA |
| Melting Point (Degree C) | 222.5 |
| Water Solubility | 3.86mg/ml at 25C |
| Drugbank ID | DB01013 |
| Receptor | P79686; Q6XLJ0; P49115; P04150; P06537; P49843; O73673; Q9N1U3; Q5R9P5; P59667; P06536; P79269; O13186; O46567; P35547; Q95267; P49844; Q3MSN1; Q3MSN4 |
| Reference | Pubchem
|