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20028 details
Primary information
ID20028
Pubchem ID5311051
NameClobetasol
DescriptionA derivative of PREDNISOLONE with high glucocorticoid activity and low mineralocorticoid activity. Absorbed through the skin faster than FLUOCINONIDE; it is used topically in treatment of PSORIASIS but may cause marked adrenocortical suppression.
Synonymclobetasol Clobecort Amex
Molecular Weight410.91
FormulaC22H28ClFO4
IUPAC(8S;9R;10S;11S;13S;14S;16S;17R)-17-(2-chloroacetyl)-9-fluoro-11;17-dihydroxy-10;13;16-trimethyl-6;7;8;11;12;14;15;16-octahydrocyclopenta[a]phenanthren-3-one
SMILECC1CC2C3CCC4=CC(=O)C=CC4(C3(C(CC2(C1(C(=O)CCl)O)C)O)F)C
PDB IDNA
KEGGD07715
HMDB IDNA
Melting Point (Degree C)NA
Water SolubilityNA
Drugbank IDNA
ReceptorP79686; Q6XLJ0; P49115; P04150; P06537; P49843; O73673; Q9N1U3; Q5R9P5; P59667; P06536; P79269; O13186; O46567; P35547; Q95267; P49844; Q3MSN1; Q3MSN4
ReferencePubchem