| Primary information |
|---|
| ID | 20003 |
| Pubchem ID | 92810 |
| Name | 5-alpha-Dihydroprogesterone |
| Description | A biologically active 5-alpha-reduced metabolite of plasma PROGESTERONE. It is the immediate precursor of 5-alpha-pregnan-3-alpha-ol-20-one (ALLOPREGNANOLONE); a neuroactive steroid that binds with GABA(A) RECEPTOR. |
| Synonym | 3;20-Allopregnanedione 5-alpha-Dihydroprogesterone 3;20-Dioxo-5alpha-pregnane 5alpha-Pregnane-3;20-dione Allopregnane-3;20-dione 5beta-Pregnane-3;20-dione |
| Molecular Weight | 316.48 |
| Formula | C21H32O2 |
| IUPAC | (5S;8R;9S;10S;13S;14S;17S)-17-acetyl-10;13-dimethyl-1;2;4;5;6;7;8;9;11;12;14;15;16;17-tetradecahydrocyclopenta[a]phenanthren-3-one |
| SMILE | CC(=O)C1CCC2C1(CCC3C2CCC4C3(CCC(=O)C4)C)C |
| PDB ID | NA |
| KEGG | C03681 |
| HMDB ID | HMDB0003759 |
| Melting Point (Degree C) | 200 |
| Water Solubility | NA |
| Drugbank ID | NA |
| Receptor | Q9GLW0; P07812; P06401; P79373; Q00175; P06186; Q8AYI2; Q63449; Q28590; Q6Q6S5; Q8NG42; Q8NG43; Q8NG44; Q8TDS3; Q8UVY3 |
| Reference | Pubchem; HMDB
|