A database of hormones and their receptors
Non-peptide Hormone

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HMRbase accession number1028
PubChem ID5311051
Hormone nameClobetasol
DescriptionA derivative of PREDNISOLONE with high glucocorticoid activity and low mineralocorticoid activity. Absorbed through the skin faster than FLUOCINONIDE, it is used topically in treatment of PSORIASIS but may cause marked adrenocortical suppression.
Synonymsclobetasol Clobecort Amex
Molecular weight410.91
Molecular formulaC22H28ClFO4
IUPAC Name(8S,9R,10S,11S,13S,14S,16S,17R)-17-(2-chloroacetyl)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-on
e
Canonical smilesCC1CC2C3CCC4=CC(=O)C=CC4(C3(C(CC2(C1(C(=O)CCl)O)C)O)F)C
Isomeric smilesC[C@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@@]4([C@]3([C@H](C[C@@]2([C@]1(C(=O)CCl)O)C)O)F)C
Structure
   
PDB file
SDF file
MOL file
PDB IDN/A
KEGG IDD07715   
HMDB IDN/A
Melting PointN/A
Log PN/A
Water SolubilityN/A
DrugBank IDN/A
Drugpediawiki
ReceptorP79686   Detail in HMRbase   
Q6XLJ0   Detail in HMRbase   
P49115   Detail in HMRbase   
P04150   Detail in HMRbase   
P06537   Detail in HMRbase   
P49843   Detail in HMRbase   
O73673   Detail in HMRbase   
Q9N1U3   Detail in HMRbase   
Q5R9P5   Detail in HMRbase   
P59667   Detail in HMRbase   
P06536   Detail in HMRbase   
P79269   Detail in HMRbase   
O13186   Detail in HMRbase   
O46567   Detail in HMRbase   
P35547   Detail in HMRbase   
Q95267   Detail in HMRbase   
P49844   Detail in HMRbase   
Q3MSN1   Detail in HMRbase   
Q3MSN4   Detail in HMRbase   
Comments!Link to Receptor is not Organism Specific
ReferencesPubchem