A database of hormones and their receptors
Non-peptide Hormone

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HMRbase accession number1021
PubChem ID9782
Hormone nameBetamethasone
DescriptionA glucocorticoid given orally, parenterally, by local injection, by inhalation, or applied topically in the management of various disorders in which corticosteroids are indicated. Its lack of mineralocorticoid properties makes betamethasone particularly suitable for treating cerebral edema and congenital adrenal hyperplasia. (From Martindale, The Extra Pharmacopoeia, 30th ed, p724)
Synonymsbetamethasone Rinderon Celestone Betadexamethasone Betafluorene Betamamallet Betamethazone Flubenisolone Betacorlan Betacortril
Molecular weight392.46
Molecular formulaC22H29FO5
IUPAC Name(8S,9R,10S,11S,13S,14S,16S,17R)-9-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-o
ne
Canonical smilesCC1CC2C3CCC4=CC(=O)C=CC4(C3(C(CC2(C1(C(=O)CO)O)C)O)F)C
Isomeric smilesC[C@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@@]4([C@]3([C@H](C[C@@]2([C@]1(C(=O)CO)O)C)O)F)C
Structure
   
PDB file
SDF file
MOL file
PDB IDN/A
KEGG IDD00244  
HMDB IDN/A
Melting Point232(EXP)
Log P1.94(EXP)
Water Solubility66.5(EXP) at 25C
DrugBank IDDB00443
Drugpediawiki
ReceptorP04150   Detail in HMRbase   
Comments
ReferencesPubchem